NAAMII invites you to the first episode of NAAMII Public Lecture Series 2020:
‘A bridge between engineering and neuroscience : Deep Brain Stimulation in Parkinson’s disease’
Speaker: Dr. Nabin Koirala, Yale University
Home Page: https://haskinslabs.org/people/nabin-koirala
Dr. Nabin Koirala completed his engineering degree from Tribhuvan University in Nepal before moving to Germany for Masters degree in Signal Processing and Digital Communications in 2012. During the period, he got interested in Biomedical signal processing and started working with brain signals. Further continuing that interest, he started his PhD in Neuroscience in 2015 from Johannes Gutenberg University, Mainz, Germany and finished it in July 2019. Since September 2019, he is in the USA pursuing his postdoctoral research at Yale University, New Haven. During his doctoral and postdoctoral tenure, he has worked extensively in various neurodegenerative and neuroinflammatory diseases providing new insights into the pathophysiology and systemic effects of the disease through the use of non-invasive neuroimaging techniques. He worked with various models of neuroimaging data expertizing in diffusion, anatomical and functional imaging analysis and several other electrophysiological data including EEG, EMG, MER and LFP. In addition to acquiring and analyzing the neuroimaging data, he has worked on further extending it to perform brain network analysis and actuated optimizing the MRI sequences to acquire the optimal data needed. Currently, in addition to the continuation and elaboration of the previous findings, he is working on large neuroimaging multicenter dataset (with up to 10,000 subjects’ data) on various techniques to analyze, optimize and associate it with various genetics and behavioral outcomes.
This talk would serve as a basic introduction to Parkinson’s disease, Deep brain stimulation and brain network analysis in general. I would give an overview of the disease, and possible treatment options and show some of my work on the field over the years. Also, I would try to invest some time in talking about neuroscience field in general and the open nature of it for making it possible for people from any background to do research in it. Parkinson’s disease is a neurodegenerative disorder that is characterized by motor and non-motor dysfunction. PD is associated with dopaminergic dysfunction and abnormal integrity of distributed brain neural networks. For the last two decades, deep brain stimulation (DBS) has been the state-of-the-art therapy for motor symptoms in PD.In the last decade, findings from magnetic resonance imaging (MRI) – T1-weighted and diffusion weighted data has been established as a standard evidenced based technique to quantify cerebral gray matter and white matter properties. These properties alone or combined with the behavioral, clinical or electrophysiological data could help us to broaden our spectrum in understanding various neurological disorders.
Date: Thursday, February 6, 2020
Time: 2:00- 4:00 pm
Venue: GATE College, Mandikhatar, Kathmandu
Facebook Event Page: https://www.facebook.com/events/170682990879125/